Neural control of the gastrointestinal tract: Implications for Parkinson disease
Identifieur interne : 002740 ( Main/Exploration ); précédent : 002739; suivant : 002741Neural control of the gastrointestinal tract: Implications for Parkinson disease
Auteurs : Maria G. Cersosimo [Argentine] ; Eduardo E. Benarroch [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-06-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Anal Canal (innervation), Constipation, Dysphagia, Enteric Nervous System (physiopathology), Esophageal Motility Disorders (physiopathology), Gastric Emptying (physiology), Gastrointestinal Diseases (physiopathology), Gastrointestinal Motility (physiology), Gastrointestinal Tract (innervation), Gastrointestinal diseases, Humans, Lewy Body Disease (physiopathology), Lewy bodies, Lewy body, Medulla Oblongata (physiopathology), Muscle, Skeletal (innervation), Muscle, Smooth (innervation), Nerve Net (physiopathology), Nervous system, Nervous system diseases, Parasympathetic Nervous System (physiopathology), Parkinson Disease (physiopathology), Parkinson disease, Spinal Cord (physiopathology), Sympathetic Nervous System (physiopathology), Vagus Nerve (physiopathology), constipation, dysphagia, enteric nervous system, vagal nuclei.
- MESH :
- innervation : Anal Canal, Gastrointestinal Tract, Muscle, Skeletal, Muscle, Smooth.
- physiology : Gastric Emptying, Gastrointestinal Motility.
- physiopathology : Enteric Nervous System, Esophageal Motility Disorders, Gastrointestinal Diseases, Lewy Body Disease, Medulla Oblongata, Nerve Net, Parasympathetic Nervous System, Parkinson Disease, Spinal Cord, Sympathetic Nervous System, Vagus Nerve.
- Humans.
Abstract
Disorders of swallowing and gastrointestinal motility are prominent nonmotor manifestations of Parkinson disease (PD). Motility of the gut is controlled both by extrinsic inputs from the dorsal motor nucleus of the vagus (DMV) and paravertebral sympathetic ganglia and by local reflexes mediated by intrinsic neurons of the enteric nervous system (ENS). Both the ENS and the DMV are affected by Lewy body pathology at early stages of PD. This early involvement provides insights into the pathophysiology of gastrointestinal dysmotility in this disorder and may constitute an important step in the etiopathogenesis of Lewy body disease. © 2008 Movement Disorder Society.
Url:
DOI: 10.1002/mds.22051
Affiliations:
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Le document en format XML
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Motility of the gut is controlled both by extrinsic inputs from the dorsal motor nucleus of the vagus (DMV) and paravertebral sympathetic ganglia and by local reflexes mediated by intrinsic neurons of the enteric nervous system (ENS). Both the ENS and the DMV are affected by Lewy body pathology at early stages of PD. This early involvement provides insights into the pathophysiology of gastrointestinal dysmotility in this disorder and may constitute an important step in the etiopathogenesis of Lewy body disease. © 2008 Movement Disorder Society.</div></front></TEI><affiliations><list><country><li>Argentine</li><li>États-Unis</li></country><region><li>Minnesota</li></region></list><tree><country name="Argentine"><noRegion><name sortKey="Cersosimo, Maria G" sort="Cersosimo, Maria G" uniqKey="Cersosimo M" first="Maria G." last="Cersosimo">Maria G. 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